Description

2-Methoxy-5-(Trifluoromethoxy)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, distinguished by its unique trifluoromethoxy and methoxy substituents. This compound is a critical pharmaceutical intermediate and advanced building block for the synthesis of complex molecules, offering enhanced metabolic stability and lipophilicity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds used in display technologies.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and as a precursor for more complex fluorinated molecules.
• Polymer Modification: Can be incorporated into polymer chains to impart specific properties like chemical resistance or altered refractive index.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1017779-14-4
Molecular Formula	C₁₁H₉F₃O₄
Molecular Weight	262.18 g/mol
Synonyms	(E)-3-[2-Methoxy-5-(trifluoromethoxy)phenyl]acrylic acid; 3-(2-Methoxy-5-(trifluoromethoxy)phenyl)-2-propenoic acid; 2-Methoxy-5-(trifluoromethoxy)cinnamic acid; (E)-2-Methoxy-α-[(trifluoromethoxy)methylene]benzenepropanoic acid; Trifluoromethoxy Cinnamic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of 2-Methoxy-5-(Trifluoromethoxy)Cinnamic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.