Description

3-Chloro-4-Ethoxy-5-Fluorobenzoic Acid is a high-purity, multi-functional benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of chloro, ethoxy, and fluoro substituents, which enable precise molecular modifications for developing novel compounds with targeted properties. This intermediate is essential for research and production teams in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and sophisticated crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing complex organic molecules used in electronic displays and optoelectronic devices.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex aromatic systems via coupling reactions, esterifications, and amide formations.
• Chemical Research & Development: A valuable reagent for exploring new chemical reactions and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	3-Chloro-4-Ethoxy-5-Fluorobenzoic Acid
CAS No.	1017778-72-1
Molecular Formula	C9H8ClFO3
Molecular Weight	218.61 g/mol
Synonyms	5-Fluoro-3-chloro-4-ethoxybenzoic acid; 4-Ethoxy-3-chloro-5-fluorobenzoic acid; Benzoic acid, 3-chloro-4-ethoxy-5-fluoro-; 3-Chloro-4-ethoxy-5-fluorobenzoic acid; 1017778-72-1
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Ethoxy-5-Fluorobenzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full transparency and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.