Description

4,5-Difluoro-m-Toluic Acid, 5-Carboxy-2,3-Difluorotoluene is a high-value, multi-fluorinated aromatic carboxylic acid building block essential for advanced organic synthesis. Its unique structure, featuring a carboxylic acid group and two strategically placed fluorine atoms on the toluene backbone, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluorotoluene moiety enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify polarity and mesomorphic properties.
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Electronic Materials: Utilized in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors, where fluorine substitution improves electron affinity and device efficiency.
• Chemical Research & Development: A versatile building block for medicinal chemistry, process chemistry, and material science research, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	4,5-Difluoro-m-Toluic Acid, 5-Carboxy-2,3-Difluorotoluene
CAS No.	1017778-60-7
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	5-Carboxy-2,3-difluorotoluene; 2,3-Difluoro-5-methylbenzoic Acid; 3-Methyl-4,5-difluorobenzoic Acid; 4,5-Difluoro-3-methylbenzoic Acid; m-Toluic Acid, 4,5-difluoro-; Benzoic acid, 4,5-difluoro-3-methyl-; 1017778-60-7; 5-Methyl-2,3-difluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-m-Toluic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical and advanced material research. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.