Description

2-Fluoro-4,6-Bis(trifluoromethyl)phenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring multiple fluorine atoms and a reactive acetic acid side chain, makes it a critical intermediate for developing novel compounds with enhanced properties. This product is primarily targeted at R&D and production teams in the pharmaceutical, agrochemical, and specialty materials industries seeking to incorporate sophisticated fluorinated motifs into their molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and metabolic diseases where fluorination improves bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms contribute to increased lipophilicity, membrane permeability, and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, enhancing charge transport, thermal stability, and optical properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique characteristics such as chemical resistance, low surface energy, and improved weatherability.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions and for introducing the 2-fluoro-4,6-bis(trifluoromethyl)phenyl moiety into complex molecular architectures.

Basic Information

Product Name	2-Fluoro-4,6-Bis(trifluoromethyl)phenylacetic Acid
CAS No.	1017778-54-9
Molecular Formula	C11H5F7O2
Molecular Weight	302.14 g/mol
Synonyms	2-Fluoro-α,α-bis(trifluoromethyl)benzeneacetic Acid; [2-Fluoro-4,6-bis(trifluoromethyl)phenyl]acetic Acid; 4,6-Bis(trifluoromethyl)-2-fluorophenylacetic Acid; 2-Fluoro-4,6-bis(trifluoromethyl)benzenecetic Acid; α-(2-Fluoro-4,6-bis(trifluoromethyl)phenyl)acetic Acid; 1017778-54-9; F4CF3PA
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4,6-Bis(trifluoromethyl)phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.