Description

2-Methyl-5-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, distinguished by its trifluoromethyl and methyl substituents which impart unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions, as well as for creating libraries of fluorinated compounds for screening.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances where specific fluorination patterns are required.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Cinnamic Acid
CAS No.	1017778-08-3
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	(E)-3-[2-Methyl-5-(trifluoromethyl)phenyl]acrylic acid; 3-(2-Methyl-5-(trifluoromethyl)phenyl)-2-propenoic acid; 2-Methyl-5-(trifluoromethyl)cinnamate; α-Methyl-3-(trifluoromethyl)cinnamic acid; 5-(Trifluoromethyl)-2-methylcinnamic acid; (E)-2-Methyl-5-(trifluoromethyl)cinnamic acid; trans-2-Methyl-5-(trifluoromethyl)cinnamic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Cinnamic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.