Description

2-Methyl-3-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated organic building block characterized by its cinnamic acid core structure with methyl and trifluoromethyl substituents. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting inflammation, CNS disorders, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of advanced electronic materials for displays and lighting applications.
• Organic Synthesis & Chemical Research: A versatile reagent for constructing complex fluorinated molecules in academic and industrial R&D laboratories.
• Advanced Polymer Chemistry: Can be incorporated as a monomer or modifier to create specialty polymers with unique thermal and chemical resistance properties.

Basic Information

Product Name	2-Methyl-3-(Trifluoromethyl)Cinnamic Acid
CAS No.	1017777-95-5
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	(E)-3-[2-Methyl-3-(trifluoromethyl)phenyl]acrylic acid; 3-(2-Methyl-3-(trifluoromethyl)phenyl)-2-propenoic acid; 2-Methyl-α,3-bis(trifluoromethyl)cinnamic acid (common misnomer); 2-Methyl-3-trifluoromethylcinnamic acid; (2E)-3-[2-Methyl-3-(trifluoromethyl)phenyl]prop-2-enoic acid; MFCD23123081; 1017777-95-5
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(Trifluoromethyl)Cinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.