Description

2-Fluoro-5-(Trifluoromethoxy)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethoxy substituents, imparts desirable properties such as enhanced metabolic stability and lipophilicity to final compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Building block for developing next-generation herbicides and pesticides with improved efficacy and environmental profiles.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Serves as a monomer or intermediate in the synthesis of materials for OLEDs and organic semiconductors.
• Chemical Research & Development: A versatile reagent for exploring new fluorination chemistry and constructing complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of tailored compounds for client-specific projects.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1017777-31-9
Molecular Formula	C₁₀H₆F₄O₃
Molecular Weight	250.15 g/mol
Synonyms	(E)-3-[2-Fluoro-5-(trifluoromethoxy)phenyl]acrylic acid; 2-Fluoro-5-(trifluoromethoxy)cinnamic acid; (2E)-3-[2-Fluoro-5-(trifluoromethoxyl)phenyl]-2-propenoic acid; trans-2-Fluoro-5-(trifluoromethoxy)cinnamic acid; α-Fluoro-β-[2-fluoro-5-(trifluoromethoxy)phenyl]acrylic acid; FTCA; 2-F-5-TFMCA
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(Trifluoromethoxy)Cinnamic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemical intermediates. A detailed Certificate of Analysis (COA) documenting purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.