Description

7A-(4-Fluorophenyl)-5-Oxohexahydropyrrolo[2,1-B][1,3]Thiazole-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within central nervous system (CNS) and anti-infective drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of lead compounds.
• API Development: Serves as a critical precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Chemical Biology Probes: Can be utilized to develop specialized molecular probes for studying enzyme function or receptor interactions in biological systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.

Basic Information

Product Name	7A-(4-Fluorophenyl)-5-Oxohexahydropyrrolo[2,1-B][1,3]Thiazole-3-Carboxylic Acid
CAS No.	1009269-94-6
Molecular Formula	C14H13FN2O3S
Molecular Weight	308.33 g/mol
Synonyms	7a-(4-Fluorophenyl)-5-oxohexahydro-2H-pyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid; Hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid, 7a-(4-fluorophenyl)-5-oxo-; 7a-(4-Fluorophenyl)-5-oxo-2,3,5,6,7,7a-hexahydropyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid; (3S,7aR)-7a-(4-Fluorophenyl)-5-oxohexahydro-2H-pyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid; (3R,7aS)-7a-(4-Fluorophenyl)-5-oxohexahydro-2H-pyrrolo[2,1-b][1,3]thiazole-3-carboxylic acid; CAS 1009269-94-6
EINECS	Contact for details

Quality Control

Our production of 7A-(4-Fluorophenyl)-5-Oxohexahydropyrrolo[2,1-B][1,3]Thiazole-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D applications. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.