Description

Methyl 2-Cyano-4-Fluoro-5-Methoxybenzoate is a high-purity, multi-functional benzoate ester derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic combination of electron-withdrawing cyano and fluoro groups with the methoxy substituent, making it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating novel organic electronic materials due to its conjugated system and substituent effects on electronic properties.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and functional pigments where the cyano group aids in chromophore development.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	Methyl 2-Cyano-4-Fluoro-5-Methoxybenzoate
CAS No.	1007455-23-3
Molecular Formula	C10H8FNO3
Molecular Weight	209.18 g/mol
Synonyms	Benzoic acid, 2-cyano-4-fluoro-5-methoxy-, methyl ester; Methyl 2-cyano-4-fluoro-5-methoxybenzoate; 4-Fluoro-5-methoxy-2-cyanobenzoic acid methyl ester; 2-Cyano-4-fluoro-5-methoxybenzoic acid methyl ester; Methyl 4-fluoro-5-methoxy-2-cyanobenzoate; 1007455-23-3; Methyl 2-cyano-4-fluoro-5-methoxybenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Cyano-4-Fluoro-5-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.