Description

3,5-Difluoro-2-Methylbenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and a methyl group on the aromatic ring, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro-methylbenzoate moiety enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex, fluorinated biaryl systems.
• Fluorinated Dye & Pigment Intermediate: Used in the synthesis of specialty dyes and pigments with enhanced lightfastness and color properties.

Basic Information

Item	Details
Product Name	3,5-Difluoro-2-Methylbenzoic Acid
CAS No.	1003710-06-2
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2-Methyl-3,5-difluorobenzoic Acid; 3,5-Difluoro-o-toluic Acid; Benzoic acid, 3,5-difluoro-2-methyl-; 3,5-Difluoro-2-methyl-benzoic acid; 1003710-06-2 (CAS); 2-Methyl-3,5-difluorobenzoate; 3,5-Difluoro-2-methylbenzoate
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.