Description

4-Cyano-2-Fluoro-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique combination of electron-withdrawing groups, making it a critical intermediate for constructing complex molecules with tailored properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its nitro and cyano functionalities.
• Material Science Research: Serves as a precursor for organic electronic materials, including non-linear optical (NLO) chromophores and specialty polymers.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized azo dyes and high-performance pigments.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Cyano-2-Fluoro-5-Nitrobenzoic Acid
CAS No.	1003709-73-6
Molecular Formula	C8H3FN2O4
Molecular Weight	210.12 g/mol
Synonyms	2-Fluoro-5-nitro-4-cyanobenzoic acid; Benzoic acid, 4-cyano-2-fluoro-5-nitro-; 4-Cyano-2-fluoro-5-nitrobenzoic acid; 5-Nitro-2-fluoro-4-cyanobenzoic acid; 2-Fluoro-4-cyano-5-nitrobenzoic acid; 4-Carboxy-2-fluoro-5-nitrobenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Cyano-2-Fluoro-5-Nitrobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.