Description

4-Methoxy-2,3,5-Trifluorobenzoic Acid is a high-value fluorinated aromatic building block, essential for introducing specific steric and electronic properties into advanced molecular architectures. Its trifluoromethyl and methoxy substituents make it a critical intermediate in the synthesis of complex, biologically active compounds. This material is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Organic Electronic Materials: A building block for electron-transport materials and semiconductors in OLEDs and organic photovoltaics.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: A versatile reagent in medicinal chemistry and material science for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Item	Detail
Product Name	4-Methoxy-2,3,5-Trifluorobenzoic Acid
CAS No.	1003709-67-8
Molecular Formula	C8H5F3O3
Molecular Weight	206.12 g/mol
Synonyms	2,3,5-Trifluoro-4-methoxybenzoic Acid; 4-Methoxy-2,3,5-trifluorobenzoic Acid; Benzoic acid, 2,3,5-trifluoro-4-methoxy-; 2,3,5-Trifluoro-4-methoxybenzoic acid; 4-Methoxy-2,3,5-trifluorobenzoic acid (CAS 1003709-67-8)
EINECS	Contact for details

Quality Control

Every batch of 4-Methoxy-2,3,5-Trifluorobenzoic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting compliance with cGMP and ICH guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.