Description

2-Bromo-5-Fluoro-4-Methylbenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative. This compound serves as a critical pharmaceutical intermediate and organic synthesis building block, prized for its unique substitution pattern that enables selective chemical transformations. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging the bromo and fluoro substituents for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Monomer: Can be incorporated into polymers and liquid crystals to modify thermal stability, solubility, and electronic properties.
• Organic Electronic Materials: Potential use in the development of organic semiconductors and charge-transport materials.
• Custom Synthesis and R&D: Employed in academic and industrial research laboratories for method development and exploring new chemical space.

Basic Information

Product Name	2-Bromo-5-Fluoro-4-Methylbenzoic Acid
CAS No.	1003709-54-3
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	4-Methyl-2-bromo-5-fluorobenzoic Acid; 5-Fluoro-2-bromo-4-methylbenzoic Acid; 2-Bromo-5-fluoro-p-toluic Acid; Benzoic acid, 2-bromo-5-fluoro-4-methyl-; 1003709-54-3; 2-Br-5-F-4-Me-BA
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-4-Methylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.