Description

4-Fluoro-1-Hydroxy-2-Naphthoic Acid is a fluorinated naphthoic acid derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both a carboxylic acid and a phenolic hydroxyl group adjacent to a fluorine atom, makes it a critical building block for creating complex molecules with tailored properties. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, pesticides, and fungicides, where the fluorine atom can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic semiconductors, charge-transport materials, and liquid crystal compounds used in display technologies.
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments, where its structure contributes to color fastness and unique spectral properties.
• Coordination Chemistry & Ligand Design: Acts as a chelating ligand for metal ions in catalytic systems or for creating metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	4-Fluoro-1-Hydroxy-2-Naphthoic Acid
CAS No.	1000386-61-7
Molecular Formula	C11H7FO3
Molecular Weight	206.17 g/mol
Synonyms	1-Hydroxy-4-fluoro-2-naphthoic acid; 4-Fluoro-1-hydroxy-2-naphthalenecarboxylic acid; 2-Naphthalenecarboxylic acid, 4-fluoro-1-hydroxy-; 4-Fluoro-1-naphthol-2-carboxylic acid; 4-F-1-OH-2-NA; 4-Fluoro-1H-2-naphthoic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1-Hydroxy-2-Naphthoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.