Description

2-Methylsulfonyl-5-(Trifluoromethyl)Benzoicacid is a high-value, multi-functional aromatic carboxylic acid derivative, distinguished by its trifluoromethyl and methylsulfonyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, enabling the development of novel compounds with enhanced biological activity and physicochemical properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate these privileged motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-inflammatory agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up services for clients requiring bespoke fluorinated compounds.

Basic Information

Product Name	2-Methylsulfonyl-5-(Trifluoromethyl)Benzoicacid
CAS No.	1000339-64-9
Molecular Formula	C9H7F3O4S
Molecular Weight	268.21 g/mol
Synonyms	5-(Trifluoromethyl)-2-(methylsulfonyl)benzoic acid; 2-Methanesulfonyl-5-(trifluoromethyl)benzoic acid; Benzoic acid, 5-(trifluoromethyl)-2-(methylsulfonyl)-; 2-(Methylsulfonyl)-5-(trifluoromethyl)benzoic acid; α,α,α-Trifluoro-2-methylsulfonyl-p-toluic acid
EINECS	Contact for details

Quality Control

Our production of 2-Methylsulfonyl-5-(Trifluoromethyl)Benzoicacid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.