Description

Benzoyl Chloride, 4-Cyano-2,5-Difluoro- (9Ci) is a high-value, multi-functional chemical intermediate characterized by its reactive benzoyl chloride core and strategically placed cyano and fluoro substituents. This molecular architecture makes it a critical building block for the synthesis of complex, performance-driven molecules, offering chemists precise control over electronic and steric properties. It is primarily sought after by research and development teams and production chemists in the pharmaceutical and advanced materials sectors who require a reliable, high-purity reagent to drive innovation in their synthetic pathways.

Application

This specialized benzoyl chloride derivative is engineered for advanced synthetic applications, serving as a key precursor in several high-tech industries.

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated and nitrile-containing motifs for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluoro and cyano groups contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and cyano-substituted aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific properties such as chemical resistance, thermal stability, or altered solubility.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex heterocycles and functionalized aromatic systems in medicinal and materials chemistry.

Basic Information

Product Name	Benzoyl Chloride, 4-Cyano-2,5-Difluoro- (9Ci)
CAS No.	198280-44-3
Molecular Formula	C8H2ClF2NO
Molecular Weight	201.56 g/mol
Synonyms	4-Cyano-2,5-difluorobenzoyl chloride; 2,5-Difluoro-4-cyanobenzoyl chloride; Benzoyl chloride, 4-cyano-2,5-difluoro-; 4-Cyanobenzoyl chloride, 2,5-difluoro-; (4-Cyano-2,5-difluorophenyl)methanone chloride
EINECS	Contact for details

Quality Control

Our production of Benzoyl Chloride, 4-Cyano-2,5-Difluoro- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical processes. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and our quality system supports compliance with cGMP and ISO standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.