Description

Vancomycin Hydrochloride is a potent glycopeptide antibiotic used to combat serious, life-threatening infections caused by Gram-positive bacteria. Its primary value lies in its efficacy against methicillin-resistant *Staphylococcus aureus* (MRSA) and other multidrug-resistant organisms, making it a critical last-line therapeutic agent. This high-purity active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry formulating injectable solutions, capsules, and other sterile dosage forms for hospital and clinical use.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for systemic treatment of severe infections.
• Antibiotic Resistance Treatment: Key therapeutic for infections caused by MRSA (Methicillin-resistant *Staphylococcus aureus*) and other resistant Gram-positive bacteria.
• Hospital-Acquired Infection Control: Used in the management of complicated skin infections, bloodstream infections, endocarditis, and meningitis.
• Oral Formulations: Incorporated into capsule or solution forms for the treatment of *Clostridioides difficile*-associated colitis.
• Research & Development: Serves as a reference standard and critical reagent in microbiological research, antibiotic susceptibility testing, and new drug development studies.
• Veterinary Medicine: Used in specialized veterinary pharmaceuticals for treating serious bacterial infections in animals.

Basic Information

Product Name	Vancomycin Hydrochloride
CAS No.	197638-25-8
Molecular Formula	C66H75Cl2N9O24 · HCl
Molecular Weight	Approx. 1485.7 g/mol
Synonyms	Vancomycin HCl; Vancocin Hydrochloride; Vancomycin Monohydrochloride; (1S,2R,18R,19R,22S,25R,28R,40S)-22-(Carbamoylmethyl)-5,47-dichloro-2,18,32,35,37-pentahydroxy-19-[(2R)-4-methyl-2-(methylamino)pentanamido]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2³,⁶.2¹⁴,¹⁷.1⁸,¹².1²⁹,³³.0¹⁰,²⁵.0³⁴,³⁹]tetratetraconta-3,5,8,10,12,14,16,29,31,33,35,37,39-tridecaene-40-carboxylic acid hydrochloride; Antibiotic M 05865; Vancor; Lyphocin
EINECS	Contact for details

Quality Control

Our Vancomycin Hydrochloride is manufactured and tested under strict quality systems to ensure it meets the stringent requirements for pharmaceutical active ingredients. Each batch undergoes comprehensive analytical testing, including assay, purity profiling, and impurity quantification via HPLC, in compliance with current pharmacopeial standards (e.g., USP, EP). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, potency, and safety parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC, anhydrous basis)	95.0% - 102.0%
pH (1% solution)	2.5 - 4.5
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%
Bacterial Endotoxins	< 0.25 EU/mg (for injectable grade)
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.