Description

α-Methyl-3-(Benzoyl) Benzyl Penicillin Sodium is a semi-synthetic penicillin derivative, specifically a penicillinase-resistant penicillin sodium salt. This compound is significant for its role as a key intermediate in the synthesis of advanced β-lactam antibiotics, offering a crucial building block for pharmaceutical research and development. It is primarily needed by manufacturers and research institutions in the pharmaceutical and fine chemical sectors engaged in antibiotic development and production.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel penicillin and β-lactam antibiotic compounds.
• Antibiotic Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new antimicrobial agents.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a building block in multi-step synthetic routes for producing complex antibiotic APIs.
• Biochemical Research: Employed in studies investigating bacterial resistance mechanisms, particularly those involving β-lactamases.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	α-Methyl-3-(Benzoyl) Benzyl Penicillin Sodium
CAS No.	196309-79-2
Molecular Formula	C23H21N2NaO5S
Molecular Weight	460.48 g/mol
Synonyms	6-[(2-Methyl-3-benzoylphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt; Sodium (2S,5R,6R)-6-[[(2-Methyl-3-benzoylphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 3-Benzoyl-α-methylbenzylpenicillin sodium; Penicillin sodium derivative 196309-79-2; Antibiotic intermediate 196309-79-2
EINECS	Contact for details

Quality Control

Our α-Methyl-3-(Benzoyl) Benzyl Penicillin Sodium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical research and intermediate use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and potency. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
pH (10% solution)	5.5 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.