Description

4-Bromo-2,3-Difluorobenzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique halogenated and fluorinated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoro motif enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores used in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with specific thermal, chemical, or surface properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Bromo-2,3-Difluorobenzoic Acid
CAS No.	194804-91-6
Molecular Formula	C7H3BrF2O2
Molecular Weight	236.99 g/mol
Synonyms	2,3-Difluoro-4-bromobenzoic Acid; Benzoic acid, 4-bromo-2,3-difluoro-; 4-Bromo-2,3-difluorobenzoic acid; 194804-91-6; 4-Br-2,3-F2BA; 2,3-Difluoro-4-bromobenzoic acid; 4-Bromo-2,3-difluoro-benzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,3-Difluorobenzoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.