Description

2,3,6-Trifluorobenzoyl Chloride is a high-purity fluorinated aromatic acid chloride building block essential for advanced organic synthesis. Its value lies in introducing the trifluoromethylbenzoyl moiety, which is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This intermediate is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for display technologies.
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, altering material properties like chemical resistance and thermal stability.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions to form amides and esters.
• Chemical Research & Development: Fundamental material for exploring new fluorinated compounds in academic and industrial R&D settings.

Basic Information

Product Name	2,3,6-Trifluorobenzoyl Chloride
CAS No.	189807-20-3
Molecular Formula	C7H2ClF3O
Molecular Weight	194.54 g/mol
Synonyms	2,3,6-Trifluorobenzoyl chloride; 2,3,6-Trifluorobenzoic acid chloride; Benzoyl chloride, 2,3,6-trifluoro-; 189807-20-3; 2,3,6-Trifluorobenzenecarbonyl chloride; α,2,3-Trifluorobenzoyl chloride; 2,3,6-Trifluoro-benzoic acid chloride
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as water, alcohols, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.