Description

5-Chloro-4-Fluoro-2-Hydroxybenzoic Acid is a high-purity, multifunctional halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring chloro, fluoro, and hydroxy substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Acts as a monomer or additive to introduce halogenated aromatic units into polymer chains, enhancing material properties like flame retardancy and chemical resistance.
• Complex Ligand Synthesis: Employed in the preparation of specialized chelating agents and ligands for catalysis and metal ion sequestration.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical reactions and synthesizing libraries of compounds for screening.

Basic Information

Product Name	5-Chloro-4-Fluoro-2-Hydroxybenzoic Acid
CAS No.	189283-52-1
Molecular Formula	C7H4ClFO3
Molecular Weight	190.56 g/mol
Synonyms	2-Hydroxy-5-chloro-4-fluorobenzoic Acid; 5-Chloro-4-fluoro-2-hydroxybenzoic acid; 4-Fluoro-5-chlorosalicylic Acid; 5-Chloro-4-fluorosalicylic Acid; Benzoic acid, 5-chloro-4-fluoro-2-hydroxy-; 189283-52-1; 4-Fluoro-5-chloro-2-hydroxybenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-4-Fluoro-2-Hydroxybenzoic Acid is produced and tested under a strict quality management system to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our partners in meeting their regulatory and compliance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.