Description

4-(2-Fluoro-4-Hydroxyphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique molecular structure, featuring both a phenolic hydroxyl and a benzoic acid group on a fluorinated biphenyl core, makes it invaluable for constructing complex molecules with tailored properties. This compound is essential for research and production in pharmaceutical development, agrochemicals, and materials science, where precise chemical functionality is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated as a monomer or additive to impart specific characteristics like thermal stability, chemical resistance, or unique optical properties to high-performance polymers.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and the creation of new chemical entities.
• Diagnostic Reagent Precursor: Utilized in the synthesis of fluorinated probes and contrast agents for biomedical imaging and diagnostic applications.

Basic Information

Product Name	4-(2-Fluoro-4-Hydroxyphenyl)Benzoic Acid
CAS No.	189161-83-9
Molecular Formula	C13H9FO3
Molecular Weight	232.21 g/mol
Synonyms	[2'-Fluoro-4'-hydroxy(1,1'-biphenyl)-4-yl]carboxylic Acid; 4'-Hydroxy-2'-fluorobiphenyl-4-carboxylic Acid; 2-Fluoro-4'-(hydroxy)biphenyl-4-carboxylic Acid; 4-(2-Fluoro-4-hydroxyphenyl)benzoic Acid; 4-Carboxy-4'-(2-fluoro-4-hydroxy)biphenyl; Biphenyl-4-carboxylic acid, 2'-fluoro-4'-hydroxy-; 189161-83-9
EINECS	Contact for details

Quality Control

Our production of 4-(2-Fluoro-4-Hydroxyphenyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.