Description

Dimethyl 2-(2-Fluoro-4-Nitrophenyl)Malonate is a high-purity, specialized organic building block featuring a fluorinated aromatic nitro group. This compound is a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique structure enables the introduction of key functional groups. It is primarily sought by research chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that require fluorinated aromatic scaffolds.
• Material Science Research: Serves as a precursor for the development of specialty polymers and advanced organic materials with tailored electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and synthesizing complex heterocyclic compounds.
• Ligand and Catalyst Development: Useful for creating novel ligands and organocatalysts used in asymmetric synthesis and other catalytic processes.

Basic Information

Item	Details
Product Name	Dimethyl 2-(2-Fluoro-4-Nitrophenyl)Malonate
CAS No.	188975-47-5
Molecular Formula	C11H10FNO6
Molecular Weight	271.20 g/mol
Synonyms	Dimethyl (2-fluoro-4-nitrophenyl)malonate; 2-(2-Fluoro-4-nitrophenyl)malonic acid dimethyl ester; Propanedioic acid, 2-(2-fluoro-4-nitrophenyl)-, dimethyl ester; (2-Fluoro-4-nitrophenyl)malonic Acid Dimethyl Ester; Dimethyl (2-Fluoro-4-Nitrobenzyl)malonate; Malonic acid, (2-fluoro-4-nitrophenyl)-, dimethyl ester; Dimethyl 2-(2-Fluoro-4-Nitrobenzyl)malonate
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(2-Fluoro-4-Nitrophenyl)Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical parameters. Our quality commitment supports applications requiring high standards, including cGMP development and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.