Description

Methyl 3-Bromo-5-(Trifluoromethyl)Benzoate is a high-purity, multi-functional aromatic ester building block essential for advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials used in displays and lighting.
• Cross-Coupling Reactions: The bromo substituent acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Negishi, and Stille couplings to create biaryl structures.
• Functional Polymer Monomer: Incorporated into polymer backbones to impart specific properties such as hydrophobicity, chemical resistance, and altered refractive indices.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Detail
Product Name	Methyl 3-Bromo-5-(Trifluoromethyl)Benzoate
CAS No.	187331-46-0
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	3-Bromo-5-(trifluoromethyl)benzoic acid methyl ester; Methyl 3-bromo-α,α,α-trifluoro-m-toluate; Benzoic acid, 3-bromo-5-(trifluoromethyl)-, methyl ester; m-Bromo-α,α,α-trifluoromethylbenzoic acid methyl ester; Methyl m-bromo-α,α,α-trifluoromethylbenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Bromo-5-(Trifluoromethyl)Benzoate is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and purity for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for pharmaceutical and advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.