Description

2,5-Dibromo-4-Fluoro-Benzoic Acid is a halogenated benzoic acid derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the strategic placement of bromine and fluorine atoms on the aromatic ring, which allows for selective further functionalization and the introduction of unique electronic properties into target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and bromine substituents can enhance potency and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating halogenated aromatic cores in advanced electronic materials for displays and lighting.
• Organic Ligand Preparation: Utilized to synthesize specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings to construct complex biaryl systems.
• Fluorine Chemistry Research: Acts as a valuable model compound for studying the influence of combined halogen substituents on chemical reactivity and physical properties.

Basic Information

Product Name	2,5-Dibromo-4-Fluoro-Benzoic Acid
CAS No.	187326-20-1
Molecular Formula	C7H3Br2FO2
Molecular Weight	297.91 g/mol
Synonyms	4-Fluoro-2,5-dibromobenzoic Acid; Benzoic acid, 2,5-dibromo-4-fluoro-; 2,5-Dibromo-4-fluorobenzoic acid; 2,5-Dibromo-4-fluoro-benzoic acid; 187326-20-1; 4-Fluoro-2,5-dibromo-benzoic acid; 2,5-Dibromo-4-fluorobenzoic acid (ACI)
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-4-Fluoro-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.