Description

4,5-Difluoro-2-Methylbenzoic Acid is a high-value fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture, featuring strategically placed fluorine atoms and a methyl group, makes it indispensable for modulating the electronic and steric properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced potency and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where fluorine incorporation improves bioactivity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in advanced display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine into polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Utilized in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and OFETs.
• Chemical Research & Development: A versatile reagent for medicinal chemistry, exploring structure-activity relationships (SAR) and developing novel fluorinated chemical entities.

Basic Information

Item	Details
Product Name	4,5-Difluoro-2-Methylbenzoic Acid
CAS No.	183237-86-7
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	2-Methyl-4,5-difluorobenzoic Acid; 4,5-Difluoro-o-toluic Acid; Benzoic acid, 4,5-difluoro-2-methyl-; 2-Methyl-4,5-difluorobenzoic acid; 4,5-Difluoro-2-methylbenzoic acid; 183237-86-7 (CAS); 4,5-Difluoro-2-methyl-benzoic acid
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our production of 4,5-Difluoro-2-Methylbenzoic Acid adheres to strict in-process controls, with final product release contingent on comprehensive analytical verification. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support customer audits and can supply material suitable for GMP or research-grade applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.