Description

Solifenacin CAS NO 180272-14-4 is a high-purity, selective muscarinic receptor antagonist used as a key active pharmaceutical ingredient (API). It is primarily valued for its therapeutic efficacy in treating overactive bladder (OAB) syndrome by reducing involuntary detrusor muscle contractions. This compound is essential for pharmaceutical manufacturers developing and producing prescription medications for urological disorders.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for overactive bladder (OAB).
• Finished Dosage Forms: Formulation into oral solid dosage forms such as tablets and capsules (e.g., VESIcare®).
• Drug Development: Serves as a reference standard and building block in preclinical and clinical research for urological therapies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for generic and branded drug production.
• Regulatory Filings: Used in the preparation of drug master files (DMFs), ANDAs (Abbreviated New Drug Applications), and other regulatory submissions.

Basic Information

Product Name	Solifenacin
CAS No.	180272-14-4
Molecular Formula	C23H26N2O2
Molecular Weight	362.47 g/mol
Synonyms	Solifenacin Succinate (common salt form); YM-905; (3R)-1-Azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate; VESIcare®; Vesicare; Solifenacinum; UNII-6V0V48PD4R
EINECS	Contact for details

Quality Control

Our Solifenacin is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure compliance with ICH guidelines and relevant pharmacopeial standards (e.g., USP, EP). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.15% Total impurities: ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.