Description

3,5-Difluoro-2-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy groups, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluoro-methoxy motif enhances biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials and emissive layer components.
• Chemical Research & Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Polymer Precursor: Can be used to introduce fluorine atoms into polymer backbones to alter material properties like chemical resistance and thermal stability.

Basic Information

Product Name	3,5-Difluoro-2-Methoxybenzoic Acid
CAS No.	180068-67-1
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2-Methoxy-3,5-difluorobenzoic Acid; 3,5-Difluoro-2-methoxybenzoic Acid; Benzoic acid, 3,5-difluoro-2-methoxy-; 180068-67-1; 3,5-Difluoro-o-anisic Acid; 2-Methoxy-3,5-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-Methoxybenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.