Description

3-Cyano-2,4-Difluorobenzoic Acid is a high-value, multi-functional aromatic building block characterized by its benzoic acid core substituted with cyano and fluorine groups. This unique structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and agrochemicals, where its difluoro and cyano motifs are leveraged to modulate biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, contributing to the molecular framework of liquid crystals and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a monomer or functionalization agent for engineering polymers with specific thermal, chemical, or surface properties.
• Organic Synthesis & Research: A versatile reagent in academic and industrial research laboratories for constructing complex heterocycles and fluorinated aromatic systems.
• Coordination Chemistry: Potential ligand for metal-organic frameworks (MOFs) or catalysts due to the carboxylic acid and cyano functional groups.

Basic Information

Product Name	3-Cyano-2,4-Difluorobenzoic Acid
CAS No.	177942-39-1
Molecular Formula	C8H3F2NO2
Molecular Weight	183.11 g/mol
Synonyms	2,4-Difluoro-3-cyanobenzoic Acid; Benzoic acid, 3-cyano-2,4-difluoro-; 3-Cyano-2,4-difluorobenzoic acid; 2,4-Difluoro-3-cyanobenzoic acid; 177942-39-1; 3-Carboxy-2,4-difluorobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Cyano-2,4-Difluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and advanced material applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.