Description

4-Bromo-2-Chloro-5-Fluorobenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its precise halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with targeted properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Electronics: Investigated as a building block for organic semiconductors and charge-transport materials due to its electron-withdrawing halogen groups.
• Chemical Biology: Employed as a probe or linker in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and proprietary development projects.

Basic Information

Product Name	4-Bromo-2-Chloro-5-Fluorobenzoic Acid
CAS No.	177480-81-8
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	2-Chloro-5-fluoro-4-bromobenzoic acid; 5-Fluoro-4-bromo-2-chlorobenzoic acid; Benzoic acid, 4-bromo-2-chloro-5-fluoro-; 4-Bromo-2-chloro-5-fluorobenzoic acid; 177480-81-8; 4-Br-2-Cl-5-F-BA
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-Chloro-5-Fluorobenzoic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.