Description

Benzoic Acid, 2-Bromo-3-(Trifluoromethyl)- is a halogenated and fluorinated derivative of benzoic acid, serving as a versatile and high-value synthetic building block. This compound is critical for introducing both bromine and trifluoromethyl functional groups into target molecules, enabling fine-tuning of electronic properties and lipophilicity. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, contributing to the molecular design of dyes, pigments, and charge-transport layers.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in organometallic chemistry for catalyst development.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new chemical spaces, structure-activity relationships (SAR), and novel fluorination methodologies.

Basic Information

Product Name	Benzoic Acid, 2-Bromo-3-(Trifluoromethyl)-
CAS No.	177420-63-2
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	2-Bromo-3-(trifluoromethyl)benzoic acid; 3-Trifluoromethyl-2-bromobenzoic acid; Benzoic acid, 2-bromo-3-(trifluoromethyl)-; 2-Bromo-alpha,alpha,α-trifluoro-m-toluic acid; 2-Bromo-3-trifluoromethylbenzoic acid; 2-Bromo-3-(trifluoromethyl)benzenecarboxylic acid; m-Toluic acid, 2-bromo-alpha,alpha,α-trifluoro-
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Bromo-3-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.