Description

4-Cyano-3-Fluorobenzoic Acid is a high-purity fluorinated aromatic building block of significant commercial and research interest. This compound is valued for its dual functional groups, which make it a versatile intermediate in advanced organic synthesis. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and cyano-substituted aromatic rings.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated benzoic acid moieties into polymers to alter thermal stability, chemical resistance, and surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, esterifications, and amide bond formations as a multifunctional aromatic acid derivative.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry and material science R&D for creating compound libraries and exploring structure-activity relationships.

Basic Information

Product Name	4-Cyano-3-Fluorobenzoic Acid
CAS No.	176508-81-9
Molecular Formula	C8H4FNO2
Molecular Weight	165.12 g/mol
Synonyms	3-Fluoro-4-cyanobenzoic Acid; Benzoic acid, 4-cyano-3-fluoro-; 4-Cyano-3-fluorobenzoic acid; 3-Fluoro-4-carboxybenzonitrile; 4-CN-3-F-C6H3-COOH
EINECS	Contact for details

Quality Control

Our production of 4-Cyano-3-Fluorobenzoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.