Description

3-(Trifluoromethoxy)Cinnamic Acid is a high-value fluorinated organic building block characterized by its cinnamic acid backbone and trifluoromethoxy substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated components for electronic display and lighting technologies.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry and material science.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of specialized fine chemicals and advanced intermediates.

Basic Information

Product Name	3-(Trifluoromethoxy)Cinnamic Acid
CAS No.	175675-63-5
Molecular Formula	C₁₀H₇F₃O₃
Molecular Weight	232.16 g/mol
Synonyms	(E)-3-[3-(Trifluoromethoxy)phenyl]acrylic acid; 3-(Trifluoromethoxy)benzeneacrylic acid; (E)-3-(3-(Trifluoromethoxy)phenyl)-2-propenoic acid; α,3-(Trifluoromethoxy)cinnamic Acid; m-Trifluoromethoxycinnamic Acid; 3-Trifluoromethoxycinnamate
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Cinnamic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.