Description

2-(Trifluoromethoxy)Terephthalic Acid is a high-value, fluorinated aromatic dicarboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a trifluoromethoxy group and two carboxylic acid functionalities, makes it indispensable for creating materials with enhanced thermal stability, chemical resistance, and specific electronic properties. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, where the trifluoromethoxy group can improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its fluorinated structure contributes to enhanced biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a rigid, polar core component in the production of advanced liquid crystals for displays and organic light-emitting diode (OLED) materials, influencing dielectric anisotropy and emission characteristics.
• High-Performance Polymer Monomer: A crucial monomer for synthesizing polyamides, polyimides, and polyesters with exceptional thermal stability, chemical resistance, and low dielectric constants, suitable for aerospace, electronics, and automotive applications.
• Metal-Organic Framework (MOF) Linker: Employed as an organic linker in the construction of MOFs for gas storage, separation, and catalysis, leveraging its multiple coordination sites and fluorinated moiety.
• Specialty Dye & Pigment Intermediate: Used in the synthesis of complex, high-value dyes and pigments where the trifluoromethoxy group alters light absorption and color fastness properties.

Basic Information

Product Name	2-(Trifluoromethoxy)Terephthalic Acid
CAS No.	175278-21-4
Molecular Formula	C9H5F3O5
Molecular Weight	250.13 g/mol
Synonyms	2-(Trifluoromethoxy)benzene-1,4-dicarboxylic acid; Terephthalic acid, 2-(trifluoromethoxy)-; 1,4-Benzenedicarboxylic acid, 2-(trifluoromethoxy)-; 2-(Trifluoromethoxy)-1,4-benzenedicarboxylic acid; 2-TFMO-TA; α,α,α-Trifluoro-p-cresol-2,5-dicarboxylic acid (derivative)
EINECS	Contact for details

Quality Control

Every batch of 2-(Trifluoromethoxy)Terephthalic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC), identity (IR, NMR), and levels of specific impurities. Our quality protocols are designed to support cGMP and ISO standards for reliable and consistent performance in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, and incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.