Description

3-Fluoroisatoic Anhydride is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, enabling the introduction of the fluorine atom to modulate biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine substituent enhances efficacy and environmental profile.
• Fluorinated Dye & Pigment Precursor: Serves as a starting material for creating specialized fluorophores and high-performance pigments with unique optical properties.
• Material Science Research: Employed in the development of novel fluorinated polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in fluorination chemistry and heterocycle synthesis.

Basic Information

Product Name	3-Fluoroisatoic Anhydride
CAS No.	174463-53-7
Molecular Formula	C8H4FNO3
Molecular Weight	181.12 g/mol
Synonyms	3-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione; 3-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione; 3-Fluoro-1,3-dihydro-2H-1,3-benzoxazine-2,4-dione; 3-Fluoroisatoic Acid Anhydride; 3-Fluoro-2,4-dioxo-1,2,3,4-tetrahydroquinazoline; 3-Fluoro-2,4(1H,3H)-quinazolinedione (tautomer); 3-Fluoroanthranilic Acid N-Carboxyanhydride
EINECS	Contact for details

Quality Control

Our 3-Fluoroisatoic Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.