Description

Benzamide, n-Butyl-4-(8-Methyl-8-Azabicyclo(3.2.1)Oct-3-Yl)-3,4,5-Trim Ethoxy-, Monohydrochloride, Endo- is a high-purity, complex organic salt with a defined stereochemistry, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in providing a sophisticated molecular scaffold essential for developing new therapeutic agents, particularly within the central nervous system (CNS) and other specialized drug classes. This compound is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality building blocks for complex molecule assembly.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a defined starting material or intermediate in the scale-up and commercial manufacturing of active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology: Utilized as a probe or tool compound in biochemical assays to study specific biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	Benzamide, n-Butyl-4-(8-Methyl-8-Azabicyclo(3.2.1)Oct-3-Yl)-3,4,5-Trim Ethoxy-, Monohydrochloride, Endo-
CAS No.	171261-29-3
Molecular Formula	C24H38N2O4 • HCl
Molecular Weight	455.03 g/mol (free base: 418.57 g/mol)
Synonyms	endo-N-n-Butyl-4-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-3,4,5-trimethoxybenzamide monohydrochloride; 3,4,5-Trimethoxy-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)benzamide, N-Butyl-, Endo-, Hydrochloride; BNTX dihydrochloride (common research alias); 8-Methyl-3-endo-[3,4,5-trimethoxybenzoyloxy]-8-azabicyclo[3.2.1]octane N-Butyl Amide Hydrochloride; Tropane Benzamide Derivative Hydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Benzamide, n-Butyl-4-(8-Methyl-8-Azabicyclo(3.2.1)Oct-3-Yl)-3,4,5-Trim Ethoxy-, Monohydrochloride, Endo- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR, and mass spectrometry for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for each lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% endo-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.