Description

2-Methyl-3-[3-(Trifluoromethyl)Phenyl]Propanoic Acid is a high-value fluorinated aromatic building block, prized for its unique structural motif that combines a phenylpropanoic acid backbone with a trifluoromethyl substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and stability.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the synthesis of complex fluorinated compounds.

Basic Information

Product Name	2-Methyl-3-[3-(Trifluoromethyl)Phenyl]Propanoic Acid
CAS No.	168833-79-2
Molecular Formula	C11H11F3O2
Molecular Weight	232.20 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]-2-methylpropanoic acid; 2-Methyl-3-(3-trifluoromethylphenyl)propionic acid; α-Methyl-3-(trifluoromethyl)hydrocinnamic acid; Benzenepropanoic acid, α-methyl-3-(trifluoromethyl)-; 168833-79-2; 2-Methyl-3-(3-(trifluoromethyl)phenyl)propanoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-3-[3-(Trifluoromethyl)Phenyl]Propanoic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via techniques like HPLC, GC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.