Description

2,4,5-Trifluoro-3-Methyl-6-Nitrobenzoyl Chloride is a high-value, multi-functional aromatic acid chloride building block. Its unique trifluoromethyl and nitro-substituted benzoyl chloride structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to introduce specific fluorine and reactive functional groups into complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in fluorinated active pharmaceutical ingredients (APIs) where fluorine atoms enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Acts as a reactive monomer or cross-linking agent to introduce fluorine-containing side chains, enhancing polymer properties like chemical resistance and thermal stability.
• Dye & Pigment Manufacturing: Intermediate for creating specialized fluorinated dyes and pigments with unique color fastness and optical properties.
• Chemical Research & Development: A versatile reagent in organic synthesis for constructing complex fluorinated aromatic scaffolds in academic and industrial R&D settings.

Basic Information

Product Name	2,4,5-Trifluoro-3-Methyl-6-Nitrobenzoyl Chloride
CAS No.	167888-41-7
Molecular Formula	C8H3ClF3NO3
Molecular Weight	261.56 g/mol
Synonyms	2,4,5-Trifluoro-3-methyl-6-nitrobenzoyl chloride; 3-Methyl-2,4,5-trifluoro-6-nitrobenzoyl chloride; 6-Nitro-2,4,5-trifluoro-3-methylbenzoyl chloride; Benzoyl chloride, 2,4,5-trifluoro-3-methyl-6-nitro-; (2,4,5-Trifluoro-3-methyl-6-nitrophenyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2,4,5-Trifluoro-3-Methyl-6-Nitrobenzoyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality system supports the needs of cGMP manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.