Description

Poly[2'-o-(2,4-Dinitrophenyl)]Poly(A)* CAS NO 165281-56-1 is a specialized, chemically modified polynucleotide derivative, designed for advanced biochemical research and diagnostic applications. This compound is critical for researchers requiring precise molecular probes or affinity ligands due to its unique, functionalized structure. It is primarily utilized in life sciences for nucleic acid hybridization studies, the development of sensitive detection assays, and as a key intermediate in synthesizing labeled oligonucleotides for genomic analysis.

Application

• Nucleic Acid Hybridization Probes: Used as a high-specificity probe in blotting techniques (Southern, Northern) and microarray analysis.
• Diagnostic Assay Development: Serves as a critical component in the design of sensitive ELISA-like or lateral flow assays for pathogen or genetic marker detection.
• Affinity Chromatography: Acts as a ligand for the purification of specific proteins, antibodies, or other biomolecules that interact with poly(A) sequences.
• Molecular Biology Research: Employed as a model compound or substrate in studies of RNA-protein interactions, translation, and polyadenylation.
• Bioconjugation Intermediate: The dinitrophenyl (DNP) moiety facilitates further conjugation to enzymes, fluorophores, or other reporter molecules for signal amplification.
• Virology and Vaccine Research: Potential use in studying viral poly(A) tails or as a component in novel vaccine adjuvant systems.

Basic Information

Product Name	Poly[2'-o-(2,4-Dinitrophenyl)]Poly(A)*
CAS No.	165281-56-1
Molecular Formula	Contact for details
Molecular Weight	Variable (Polymer)
Synonyms	DNP-Poly(A); 2'-O-(2,4-Dinitrophenyl)polyadenylic acid; Polyadenylic acid, 2'-O-(2,4-dinitrophenyl) derivative; Poly(A)-DNP conjugate; Dinitrophenylated Poly(A); Poly A (2'-O-DNP); DNP-labeled Poly(A); Chemically modified Poly(A)
EINECS	Contact for details

Quality Control

Every batch of Poly[2'-o-(2,4-Dinitrophenyl)]Poly(A)* is manufactured and tested under stringent quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade biochemicals. Certificates of Analysis (COA) detailing purity, substitution ratio, and functional performance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may degrade performance. For long-term stability, store desiccated under inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid or lyophilized powder
Identification (IR / NMR)	Conforms to structure
Assay (HPLC / UV-Vis)	≥ 90% (Poly(A) basis)
DNP Substitution Ratio	Specified per batch (e.g., 1 DNP per 5-10 nucleotides)
Solubility	Soluble in aqueous buffers, DMSO
Endotoxin Level	< 10 EU/mg (if specified for biological use)
Biopolymer Length (Average)	Contact for details (e.g., 50-500 nucleotides)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.