Description

Siamycin Ii is a specialized cyclic hexadepsipeptide antibiotic belonging to the siamycin family. This compound is of significant interest in pharmaceutical research and development due to its potent antimicrobial activity, particularly against Gram-positive bacteria. It serves as a critical reference standard and building block for researchers in the fields of medicinal chemistry, microbiology, and antibiotic discovery. The product is supplied as Siamycin Ii CAS NO 164802-69-1 to ensure precise identification and traceability for global scientific and industrial applications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of siamycin-class antibiotics in research and quality control laboratories.
• Antimicrobial Research: Serves as a key investigational compound in studies targeting drug-resistant Gram-positive bacterial infections, including MRSA.
• Medicinal Chemistry: Acts as a lead compound or a synthetic intermediate for the development of novel peptide-based antibiotics and therapeutics.
• Biochemical Studies: Utilized in mechanistic studies to understand the mode of action of depsipeptide antibiotics on bacterial cell membranes.
• Microbiology Assays: Employed in in-vitro susceptibility testing and as a control in antimicrobial activity screenings.

Basic Information

Product Name	Siamycin Ii
CAS No.	164802-69-1
Molecular Formula	C54H78N12O12
Molecular Weight	1063.28 g/mol
Synonyms	FR-900359; Siamycin II; Antibiotic FR-900359; Cyclo[L-Phe-D-alloThr-L-Leu-D-Ser(3-OH)-L-Trp-D-aThr(3-Cl)]; L-Phenylalanyl-D-allothreonyl-L-leucyl-D-seryl(3-hydroxy)-L-tryptophyl-D-allothreonyl(3-chloro) cyclic depsipeptide; FR900359; Antibiotic FR 900359
EINECS	Contact for details

Quality Control

Our Siamycin Ii is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.