Description

Siamycin I is a potent lantibiotic-class peptide antibiotic known for its unique structural features and biological activity. This compound is of significant interest for its role in combating antibiotic-resistant bacterial strains, offering a valuable tool for advanced microbiological and pharmacological research. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel antimicrobial agents and the study of bacterial cell wall biosynthesis.

Application

• Antimicrobial Research: Investigation of novel mechanisms of action against Gram-positive bacteria, including resistant strains like MRSA.
• Pharmaceutical Development: Serves as a lead compound or reference standard in the discovery and development of new antibiotic therapies.
• Biochemical Studies: Used to study bacterial cell wall synthesis inhibition and the function of lipid II as a molecular target.
• Microbiology Assays: Acts as a positive control or active agent in antimicrobial susceptibility testing and biofilm disruption studies.
• Academic Research: Fundamental research on lantibiotic structure-activity relationships and biosynthesis pathways.

Basic Information

Product Name	Siamycin I
CAS No.	164802-68-0
Molecular Formula	C84H106N18O25S4
Molecular Weight	1848.1 g/mol
Synonyms	Siamycin; 164802-68-0; Antibiotic 107891; Lantibiotic Siamycin I; Dehydroalaninyl-Siamycin I; (3S,6S,9S,12S,15S,18S,21S,24S,27S,30S,33S,36S,39S,42S,45S,48S,51S,54S,57S,60S,63S,66S,69S,72S,75S,78S,81S,84S)-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84-Octacosaazatricyclo[82.2.2.239,42]nonatetracontane-1(86),2,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73,76,79,82,87-triacontaketone
EINECS	Contact for details

Quality Control

Our Siamycin I is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for critical research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals to guarantee reliable and reproducible results for our clients.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Due to its hygroscopic (moisture-sensitive) nature, the container must be sealed under an inert atmosphere or with desiccant to maintain stability. Allow the product to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Assayed; data on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.