Description

(R)-(-)-Dbd-Py-Ncs CAS NO 163927-31-9 is a high-purity, chiral chemical intermediate featuring a reactive isothiocyanate (NCS) group. This compound is critically important for the site-specific labeling and conjugation of biomolecules, enabling advanced research and development. It is primarily needed by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions working in the fields of fluorescence-based assays, protein chemistry, and targeted drug delivery systems.

Application

• Fluorescent Probe Synthesis: Acts as a key precursor for developing chiral fluorescent dyes and labels used in bioimaging and cellular studies.
• Bioconjugation Reagent: Used for the covalent attachment of fluorescent tags to antibodies, peptides, and other proteins via amine groups.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of targeted therapeutic agents and diagnostic molecules.
• HPLC Chiral Derivatization: Employed to create diastereomeric derivatives for the analytical separation and quantification of enantiomers.
• Sensor Development: Integral in constructing chemical sensors and assay components for detecting specific biological analytes.
• Life Science Research: Facilitates advanced biochemical and pharmacological research requiring high-specificity labeling.

Basic Information

Product Name	(R)-(-)-Dbd-Py-Ncs
CAS No.	163927-31-9
Molecular Formula	C23H19N3O2S2
Molecular Weight	433.55 g/mol
Synonyms	(R)-4-(N,N-Dimethylaminosulfonyl)-7-(3-isothiocyanatopyrrolidin-1-yl)-2,1,3-benzoxadiazole; (R)-DBD-Py-NCS; (R)-(-)-7-(3-Isothiocyanatopyrrolidin-1-yl)-4-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole; DBD-Py-NCS (R enantiomer); (R)-7-(3-Isothiocyanatopyrrolidin-1-yl)-4-(dimethylaminosulfonyl)-2,1,3-benzoxadiazole; Chiral DBD fluorescent labeling reagent; (R)-Form DBD-Py-NCS
EINECS	Contact for details

Quality Control

Our (R)-(-)-Dbd-Py-Ncs is manufactured under strict quality control protocols to ensure high chiral purity and batch-to-batch consistency. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identification data. We adhere to relevant industry standards for fine chemical intermediates to support your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; desiccants are recommended for long-term storage. Keep container tightly sealed under an inert atmosphere when not in use to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.