Description

[2-(Trifluoromethyl)Phenoxy]Acetic Acid CAS NO 162922-18-1 is a specialized fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the unique combination of the phenoxyacetic acid scaffold with the electron-withdrawing trifluoromethyl group, enabling precise modulation of molecular properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require high-purity intermediates for developing novel active ingredients. Its structural features make it a key precursor for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators, where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Polymer Modification: Employed to introduce fluorinated aromatic side chains into polymers, enhancing their chemical resistance and surface properties.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial R&D for constructing complex molecules via etherification and subsequent functional group transformations.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	[2-(Trifluoromethyl)Phenoxy]Acetic Acid
CAS No.	162922-18-1
Molecular Formula	C9H7F3O3
Molecular Weight	220.15 g/mol
Synonyms	2-[(2-Trifluoromethyl)phenoxy]acetic acid; (2-Trifluoromethylphenoxy)acetic Acid; α-(2-Trifluoromethylphenoxy)acetic Acid; o-(Trifluoromethylphenoxy)acetic Acid; 2-(2-Trifluoromethylphenoxy)ethanoic Acid; 2-(α,α,α-Trifluoro-o-tolyloxy)acetic Acid; Acetic acid, 2-[(2-(trifluoromethyl)phenyl)oxy]-; 2-(2-Trifluoromethylphenoxy)acetic acid
EINECS	Contact for details

Quality Control

Our [2-(Trifluoromethyl)Phenoxy]Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.