Description

Rasagiline Mesylate is a high-purity, small-molecule active pharmaceutical ingredient (API) with the CAS registry number 161735-79-1. It is a potent, selective, and irreversible monoamine oxidase-B (MAO-B) inhibitor of significant importance in modern neurology. This compound is primarily required by pharmaceutical manufacturers and research institutions for the development and production of treatments for Parkinson's disease.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of anti-Parkinson's drugs.
• Neurological Research: Used as a reference standard and investigational compound in studies related to MAO-B inhibition and neuroprotection.
• Generic Drug Manufacturing: Serves as a critical raw material for companies producing generic versions of rasagiline-based medications.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and assay calibration (HPLC, GC).
• Preclinical Development: Utilized in pharmacological and toxicological studies during early-stage drug discovery.
• Chemical Synthesis: Acts as a key intermediate or starting material for the synthesis of novel chemical entities or derivatives.

Basic Information

Product Name	Rasagiline Mesylate
CAS No.	161735-79-1
Molecular Formula	C12H13N • CH4O3S
Molecular Weight	267.35 g/mol
Synonyms	Rasagiline Methanesulfonate; (1R)-N-(2-Propyn-1-yl)-2,3-dihydro-1H-inden-1-amine Methanesulfonate; TVP-1012; AGN-1135; Azilect (brand name API); N-Propargyl-1(R)-aminoindan Mesylate; (R)-(+)-N-Propargyl-1-aminoindan Mesylate
EINECS	Contact for details

Quality Control

Our Rasagiline Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and heavy metals is provided with every shipment. We support compliance with major pharmacopoeial standards (USP, EP) and cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Water Content (KF)	NMT 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.