Description

Methyl 3-Methyl-5-(Trifluoromethyl)Benzoate is a high-purity fluorinated aromatic ester building block of significant commercial interest. Its core value lies in the trifluoromethyl group, which imparts unique electronic and lipophilic properties critical for advanced material and pharmaceutical synthesis. This compound is essential for R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty chemical industries seeking to incorporate fluorine into complex molecular architectures. Its defined structure and purity ensure reliable performance in demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorine into polymer backbones or side chains, enhancing chemical resistance, lowering surface energy, and improving weatherability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and ester hydrolysis/transformation to access a wide array of benzoic acid derivatives.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing fluorinated dyes with altered color properties and improved fastness.

Basic Information

Product Name	Methyl 3-Methyl-5-(Trifluoromethyl)Benzoate
CAS No.	161622-18-0
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	3-Methyl-5-(trifluoromethyl)benzoic acid methyl ester; Methyl 3-methyl-5-(trifluoromethyl)benzoate; Benzoic acid, 3-methyl-5-(trifluoromethyl)-, methyl ester; Methyl m-methyl-α,α,α-trifluoro-m-toluate; 5-(Trifluoromethyl)-m-toluic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Methyl-5-(Trifluoromethyl)Benzoate adheres to a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO 9001 standards for reliable sourcing in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.