Description

4-Bromo-3-(Trifluoromethyl)Benzoic Acid is a high-purity, multi-functional aromatic building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process developers in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating fluorinated aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a monomer or cross-linking agent to engineer polymers with specific thermal, chemical, or surface properties.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to synthesize novel ligands for catalysis, including cross-coupling reactions.
• Chemical Research & Development: A versatile building block for exploratory synthesis in academic and industrial laboratories to create new chemical entities.

Basic Information

Product Name	4-Bromo-3-(Trifluoromethyl)Benzoic Acid
CAS No.	161622-14-6
Molecular Formula	C8H4BrF3O2
Molecular Weight	269.02 g/mol
Synonyms	4-Bromo-3-(trifluoromethyl)benzoic acid; 3-Trifluoromethyl-4-bromobenzoic acid; Benzoic acid, 4-bromo-3-(trifluoromethyl)-; 4-Bromo-alpha,alpha,α-trifluoro-m-toluic acid; 4-Bromo-3-trifluoromethylbenzoic acid; 4-Bromo-3-(trifluoromethyl)benzenecarboxylic acid; 161622-14-6; 4-Bromo-3-trifluoromethyl-benzoic acid
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-(Trifluoromethyl)Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.