Description

3-Fluoro-5-(Trifluoromethyl)Benzoic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a precursor for developing advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated components for electronic display materials, improving their thermal stability and electro-optical properties.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer chains, enhancing chemical resistance and lowering surface energy for specialty coatings.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new reactions and creating compound libraries via cross-coupling and derivatization reactions.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Benzoic Acid
CAS No.	161622-05-5
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	3-Fluoro-5-(trifluoromethyl)benzoic acid; 5-(Trifluoromethyl)-3-fluorobenzoic acid; m-Fluoro-α,α,α-trifluoro-m-toluic acid; Benzoic acid, 3-fluoro-5-(trifluoromethyl)-; 3-Fluoro-α,α,α-trifluoro-m-toluic acid; 161622-05-5; 3-Fluoro-5-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.