Description

Berninamycin D CAS NO 161263-50-9 is a specialized thiopeptide antibiotic belonging to the berninamycin family, characterized by its complex macrocyclic structure. This compound is of significant interest for its potent antibacterial activity, particularly against Gram-positive bacteria, making it a valuable tool for microbiological research and drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in developing novel antimicrobial agents and studying bacterial resistance mechanisms.

Application

• Antimicrobial Research: Serves as a key reference standard and active compound in studies targeting Gram-positive pathogens.
• Mechanism of Action Studies: Used to investigate the inhibition of bacterial protein synthesis, specifically targeting the ribosome.
• Drug Discovery & Development: Acts as a lead compound or a structural template for the synthesis of novel antibiotic analogs.
• Biochemical Assays: Employed in high-throughput screening and in vitro assays to evaluate antibacterial potency.
• Microbiology & Resistance Studies: Utilized to study bacterial susceptibility and the emergence of resistance to thiopeptide antibiotics.
• Pharmaceutical Reference Standard: Provides a certified material for quality control and analytical method development in antibiotic manufacturing.

Basic Information

Product Name	Berninamycin D
CAS No.	161263-50-9
Molecular Formula	C58H66N16O18S6
Molecular Weight	1443.58 g/mol
Synonyms	Berninamycin D; Antibiotic A 35512B; GE 2270 derivative; Thiopeptide antibiotic D; Berninamycin derivative D; (Contact for additional synonyms)
EINECS	Contact for details

Quality Control

Our Berninamycin D is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation. A detailed Certificate of Analysis (COA) documenting the results is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.