Description

Methyl 4-Fluoro-3-(Methylsulfonyl)Benzoate is a high-value fluorinated aromatic building block featuring both a methyl ester and a methylsulfonyl substituent. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, leveraging the bioactivity of the fluorinated benzoate structure.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactivity of the sulfonyl and ester groups.
• Chemical Research & Development: Essential for academic and industrial labs exploring new fluorinated compounds and their properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	Methyl 4-Fluoro-3-(Methylsulfonyl)Benzoate
CAS No.	160819-39-6
Molecular Formula	C9H9FO4S
Molecular Weight	232.23 g/mol
Synonyms	Benzoic acid, 4-fluoro-3-(methylsulfonyl)-, methyl ester; Methyl 4-fluoro-3-methanesulfonylbenzoate; 4-Fluoro-3-(methylsulfonyl)benzoic acid methyl ester; 3-(Methylsulfonyl)-4-fluorobenzoic acid methyl ester; MFCD 13176577; 160819-39-6; Methyl 3-(Methylsulfonyl)-4-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 4-Fluoro-3-(Methylsulfonyl)Benzoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.