Description

Methyl 3,4-Difluoro-2-Methylbenzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its role in introducing difluoromethyl and benzoate functionalities into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the difluoro and methyl ester groups contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Organic Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Custom Chemical & Contract Manufacturing: Supplied to fine chemical companies for custom synthesis projects and scale-up production.
• Academic & Industrial R&D: A valuable reagent for methodological studies in fluorination chemistry and ester functionalization.

Basic Information

Product Name	Methyl 3,4-Difluoro-2-Methylbenzoate
CAS No.	160775-14-4
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	3,4-Difluoro-2-methylbenzoic acid methyl ester; Methyl 3,4-difluoro-o-toluate; 2-Methyl-3,4-difluorobenzoic acid methyl ester; Benzoic acid, 3,4-difluoro-2-methyl-, methyl ester; Methyl 2-methyl-3,4-difluorobenzoate; 160775-14-4; 3,4-Difluoro-2-methyl methylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 3,4-Difluoro-2-Methylbenzoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment. We support compliance with global regulatory frameworks, including REACH and TSCA.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.